FIELD: medicine, immunology. SUBSTANCE: invention relates to application of Mycobacterium vaccae for feedback inhibition regulation of Th2-activity of immune system. Method involves application of killed cells of Mycobacterium vaccae or their derivatives no containing any antigen, immunogen or allergen and no relating to M. vaccae for treatment of disorder that is characterized by stimulation of Th2-activity of immune system by decrease of Th2-activity being without stimulation of Th1-activity of immune system, namely, for treatment of disorders associated with chronic fatigue syndrome, Persian Gulf war syndrome or total allergy syndrome. The advantage of invention involves the shift of patient immune system from Th1-activity to Th2-activity using the preparation without "foreign" antigen or immunogen. EFFECT: valuable properties of preparation. 9 cl, 10 dwg
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