PURIFIED COAT PROTEINS OF HEPATITIS C VIRUS FOR DIAGNOSTIC AND THERAPEUTIC APPLICATION Russian patent published in 2008 - IPC A61K39/29 C07K14/18 G01N33/68 A61P31/14

Abstract RU 2319505 C2

FIELD: medicine.

SUBSTANCE: the present innovation deals with therapeutic vaccinal compositions that include coat protein E1 of hepatitis C virus or its immunogenic part for reducing the development of hepatic fibrosis, for reducing steatosis in mammals being chronically infected with hepatitis C virus. The present innovation , also, refers to diagnostic application of these compositions. The advantage of the innovation is based upon the usage of protein and peptides E1 of hepatitis C virus for predicting and monitoring clinical efficiency and/or clinical therapeutic result against hepatitis C virus.

EFFECT: higher efficiency.

16 cl, 57 dwg, 21 ex, 17 tbl

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RU 2 319 505 C2

Authors

Martens Gert

Depla Ehrik

Bosman Fons

Dates

2008-03-20—Published

2002-12-18—Filed