FIELD: medicine.
SUBSTANCE: invention concerns area of medicine and concerns therapeutic and preventive vaccines against hepatitis B and HIV. The essence of the invention: the offered composition includes a superficial antigen of hepatitis B (HBsAg) as the main component, received as a recombinant product of Pichia pastoris and the vaccine antigen representing polypeptide CR3, containing epitopic determinants of a human immunodeficiency virus. The offered composition can be applied at HIV treatment and during too time as a preventive vaccine against the virus of hepatitis B.
EFFECT: working out of a composition which can be applied at treatment HIV and during too time as a preventive vaccine against the virus of hepatitis B.
3 cl, 5 dwg, 7 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PRODUCTION OF ANTIGEN AGGREGATES AND USES THEREOF IN PHARMACEUTICALS | 2001 |
|
RU2266754C2 |
| VACCINAL COMPOSITION AGAINST HEPATITIS C VIRUS | 2005 |
|
RU2351363C2 |
| VACCINE COMPOSITION POTENTIATED WITH DNA AND ANTIGEN COMBINATION | 2002 |
|
RU2294212C2 |
| METHOD OF PREPARING SURFACE ANTIGEN OF HEPATITIS B VIRUS (HBS AG), MONOCLONAL ANTIBODIES CB-HEPI, SURFACE ANTIGEN OF HEPATITIS B VIRUS (HBS AG) AND METHOD OF PREPARING HYBRID CLONE 48/1/574 PRODUCING MONOCLONAL ANTIBODIES CB-HEPI | 1992 |
|
RU2128707C1 |
| IMMUNOSTIMULATING OLIGONUCLEOTIDES | 2009 |
|
RU2477753C2 |
| POLYEPITOPIC ANTI-HEPATITIS B VACCINE OF 4-TH GENERATION AND METHOD OF OBTAINING IT | 2011 |
|
RU2469741C1 |
| IMMUNOSTIMULATORY OLIGONUCLEOTIDES | 2012 |
|
RU2610690C2 |
| AGENTS AND METHODS OF TREATING HEPATITIS B VIRUS | 2017 |
|
RU2740802C2 |
| CR3 CHIMERA GENE AND CR3 CHIMERA PROTEIN ENCODED THEREWITH (VARIANTS) INDUCING ANTI-HIV-1 IMMUNE RESPONSE | 2002 |
|
RU2302461C2 |
| COMPOSITION FOR TREATING HEPATITIS B VIRUS INFECTIONS | 2010 |
|
RU2555346C2 |
