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2 321 407

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(51)

IPC

A61K31/5377(2006-01-01)

A61K31/4365(2006-01-01)

A61P7/12(2006-01-01)

(21) (22)

Application

2004101404/15, 2002-06-07

(24)

Start date

2002-06-07

(22)

Actual filing date

2002-06-07

(45)

Published

2008-04-10

(72)

Inventor

Shtraub AleksanderLampe TomasPernershtorfer DzhozefPertsborn EhlizabetPol'Mann JensRerig SjuzanneShlemmer Karl-Khajnts

(73)

Holder

Bajer Khel'Sker Ag

COMBINED THERAPY USING SUBSTITUTED OXAZOLIDINONES Russian patent published in 2008 - IPC A61K31/5377 A61K31/4365 A61P7/12

Abstract RU 2321407 C9

FIELD: organic chemistry, medicine, pharmacology.

SUBSTANCE: invention relates to a combination used in prophylaxis and/or treatment of thromboembolic diseases. Combination comprises N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-5-chloro-2-thiophene carboxamide of the formula (I): its pharmaceutically acceptable salts, hydrates or their mixtures and platelet aggregation inhibitor taken in subtherapeutic effective doses. Also, invention relates to a method for preparing this combination and a drug based on thereof. Proposed combination possesses the enhanced effectiveness.

EFFECT: improved and valuable medicinal properties of combination.

4 cl, 2 tbl, 176 ex

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RU 2 321 407 C9

Authors

Shtraub Aleksander

Lampe Tomas

Pernershtorfer Dzhozef

Pertsborn Ehlizabet

Pol'Mann Jens

Rerig Sjuzanne

Shlemmer Karl-Khajnts

Dates

2008-04-10—Published

2002-06-07—Filed