OXAZOLIDINONE DERIVATIVES, METHOD FOR PREPARING THEREOF (VERSIONS) AND BASED PHARMACEUTICAL COMPOSITION Russian patent published in 2011 - IPC C07D413/14 C07D417/14 C07D471/04 C07D498/04 A61K31/422 A61K31/5377 A61K31/541 A61P31/04 

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to oxazolidinone derivatives covered by general graphic formula (I) and to their pharmaceutically acceptable salts. In formula (I) R₁, R₂, R₃ and R₄ are independently chosen from a group including -H and halogen; A is chosen from a group including R₅ and R₆ are independently chosen from a group including -H, -F, -CI, -Br, -OH, alkyl(C₁-C₆), haloalkyl(C₁-C₆), alkoxygroup(C₁-C₆); R₇ is chosen from a group including -H, alkyl(C₁-C₆); either R₇ and R₅ or R₆ taken together form a cycle of 2 carbon atoms and include 1 group chosen from O which in turn can be substituted by one substitute chosen from alkyl(C₁-C₆); R₁₂ is chosen from a group including -H, -COR₁₄, -CSR₁₄, -COOR₁₄; R₁₄ is chosen from a group including alkyl (C₁-C₆), cycloalkyl(C₃-C₆), alkenyl(C₂-C₆), R₁₆, R₁₇ and R₁₈ represent -H; R₂₁ is chosen from a group including -H, alkyl(C₁-C₆); X is chosen from a group including O, S, and Y is chosen from a group including O, S, SO, SO₂, and NR₁₂; and optional substitutes of alkyl(C₁-C₆) groups can represent one or two groups chosen from the following: -OR₂₁, -CN.

EFFECT: invention refers to methods for preparing the compounds of the invention, to application of oxazolidinone derivatives for preparing a drug for treating bacterial infections and to a pharmaceutical composition for treating bacterial infections, including a therapeutically effective amount of the compound of the invention.

36 cl, 10 tbl, 44 ex