FIELD: organic chemistry, medicine. SUBSTANCE: invention relates to novel derivatives of taxane of the general formula:
where Ar means phenyl; R means phenyl or radical R5-O- where R5 means a direct or branched alkyl comprising from 1 to 8 carbon atoms with exception for tert.-butyl; R1 and R2 have similar or different values and mean hydrogen atom, radical alkyl, phenylalkyl, phenyl, alkoxyphenyl or dialkoxyphenyl; R3 means acetyl or a protective group of functional hydroxy-group; R4 means a protective group of functional hydroxy-group that can be used as intermediate compounds for synthesis of taxol, taxoter or their analogues showing antitumor or antileukemic properties. EFFECT: new derivatives of taxane ensuring to synthesize biologically active compounds.
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