FIELD: medicine, immunology, vaccine.
SUBSTANCE: invention proposes a composition, vaccine and methods for enhancing immune responses against antigens mixed with virus-like particles (VLP) that are bound with immunostimulating substances representing a nonmethylated CpG-containing oligonucleotide. Antigens in mixture with CpG-packed VLP particles can be ideal vaccines for prophylactic and therapeutic vaccination against allergy, tumors, other automolecules and chronic viral diseases.
EFFECT: valuable medicinal properties of compositions.
43 cl, 18 dwg, 28 ex
| Title | Year | Author | Number |
|---|---|---|---|
| COMPLETED VIRUS-LIKE PARTICLES | 2004 |
|
RU2375076C2 |
| CONJUGATES OF PEPTIDE Melan-A, VIRUS-LIKE PARTICLE ANALOGUE | 2004 |
|
RU2351362C2 |
| VIRUS-LIKE PARTICLES INCLUDING HYBRID PROTEIN OF AP205 BACTERIOPHAGE COAT PROTEIN AND ANTIGEN POLYPEPTIDE | 2005 |
|
RU2409667C2 |
| MODIFIED VIRUS PARTICLES OF CUCUMBER MOSAIC VIRUS | 2015 |
|
RU2706970C2 |
| CAT ALLERGEN FUSED PROTEIN AND APPLICATION THEREOF | 2006 |
|
RU2414239C2 |
| PARTICLES PACKED IN IMMUNOSTIMULATING NUCLEIC ACID THAT INTENDED FOR HYPERSENSITIVITY TREATMENT | 2006 |
|
RU2451523C2 |
| ANTIGEN MATRIX FOR TREATMENT OF BONE DISEASE | 2002 |
|
RU2322258C2 |
| CONJUGATES OF GHRELIN CARRIER | 2003 |
|
RU2325202C2 |
| PCSK9 VACCINE | 2010 |
|
RU2538162C2 |
| COMPOSITION FOR IMMUNIZATION (VARIANTS), METHOD FOR ITS PREPARING AND USING FOR TREATMENT OF ALLERGIC EOSINOPHILIC DISEASES | 2002 |
|
RU2319503C2 |
