FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions relates to the field of medicine and deals with particles packed in an immunostimulating nucleic acid and intended for treatment of allergic hypersensitivity. The composition as per the invention concept contains a virus-like particle packed in immunostimulating nucleic acids with the virus-like particle representing an RNA bacteriofague virus-like particle packed in an immunostimulating nucleic acid containing a non-methylated CpG nucleotide. The compositions proposed by the invention are to be most appropriately applied for treatment of atopic eczema, asthma and mediate IgE-allergy(Type I allergy), primarily - pollen allergy and domestic dust allergy.
EFFECT: advantage of the inventions consists in creation of a medication for treatment of hypersensitivity (predominantly - of allergic nature).
24 cl, 39 ex, 32 tbl, 6 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| COMPLETED VIRUS-LIKE PARTICLES | 2004 |
|
RU2375076C2 |
| COMPOSITIONS COMPRISING CpG-OLIGONUCLEOTIDES AND VIRUS-LIKE PARTICLES FOR USING AS ADJUVANTS | 2003 |
|
RU2322257C2 |
| CONJUGATES OF PEPTIDE Melan-A, VIRUS-LIKE PARTICLE ANALOGUE | 2004 |
|
RU2351362C2 |
| VIRUS-LIKE PARTICLES INCLUDING HYBRID PROTEIN OF AP205 BACTERIOPHAGE COAT PROTEIN AND ANTIGEN POLYPEPTIDE | 2005 |
|
RU2409667C2 |
| CH3 IGE PEPTIDE VACCINE | 2009 |
|
RU2495049C2 |
| CAT ALLERGEN FUSED PROTEIN AND APPLICATION THEREOF | 2006 |
|
RU2414239C2 |
| MODIFIED VIRUS PARTICLES OF CUCUMBER MOSAIC VIRUS | 2015 |
|
RU2706970C2 |
| INTERLEUKIN-1 CONJUGATES AND THEIR APPLICATION | 2006 |
|
RU2441067C2 |
| PACKAGING OLIGONUCLEOTIDES INTO VIRUS-LIKE PARTICLES | 2019 |
|
RU2816533C2 |
| METHODS OF PACKAGING OF OLIGONUCLEOTIDES INTO VIRUS-LIKE PARTICLES OF RNA-CONTAINING BACTERIOPHAGES | 2007 |
|
RU2476595C2 |
