FIELD: medicine, narcology, pharmacy.
SUBSTANCE: invention proposes using flumazenil representing 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazol[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester for production of drug used in treatment of cocaine abuse, abstinence syndrome from cocaine and relapse of cocaine abuse. Agent is administrated in time periods from 1 to 15 min providing administration of from 0.1 to 0.3 mg of flumazenil that represents the therapeutically effective dose for treatment of cocaine abuse (variants), corresponding drugs (variants) of flumazenil and methods for treatment (variants). In this regimen in the dose 2 mg of flumazenil for less 1 h above 55% of gamma-glutamic acid receptors are occupied. Invention provides attenuation or removing symptoms of cocaine abuse and rapid recovery of psychophysiological functions.
EFFECT: valuable properties of drug and enhanced effectiveness of treatment.
29 cl, 2 tbl
