COMPOSITIONS AND METHODS FOR TREATMENT OF ADDICTION, MENTAL DISORDERS AND NEURODEGENERATIVE DISEASE Russian patent published in 2018 - IPC A61K31/444 A61K31/5513 A61K38/08 A61K47/10 A61P25/30 

Abstract RU 2674259 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: group of inventions relates to the field of medicine and pharmaceuticals. First invention is a pharmaceutical composition for treating addiction, containing a first pharmaceutically active agent, which is metyrapol or a pharmaceutically acceptable salt thereof, and a second pharmaceutically active agent, which is benzodiazepine, prepared for oral or topical administration to a patient, where both metyrapol and benzodiazepine are present in the composition in an amount which is not effective for treating said disease when administered separately, additionally comprising a third pharmaceutically active agent which temporarily affects the blood-brain barrier, which is mannitol or bradykinin. Second invention is a method for treating a patient suffering from addiction, including identifying a patient in need of treatment and administering said composition to the patient.

EFFECT: compositions and methods for treating addiction, mental disorders and neurodegenerative disease are disclosed.

5 cl, 5 ex

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RU 2 674 259 C2

Authors

Geders Nikolas E.

Foks Barbara S.

Gerin Glenn

Dates

2018-12-06Published

2011-06-16Filed