FIELD: medicine; pharmaceuticals.
SUBSTANCE: group of inventions relates to the field of medicine and pharmaceuticals. First invention is a pharmaceutical composition for treating addiction, containing a first pharmaceutically active agent, which is metyrapol or a pharmaceutically acceptable salt thereof, and a second pharmaceutically active agent, which is benzodiazepine, prepared for oral or topical administration to a patient, where both metyrapol and benzodiazepine are present in the composition in an amount which is not effective for treating said disease when administered separately, additionally comprising a third pharmaceutically active agent which temporarily affects the blood-brain barrier, which is mannitol or bradykinin. Second invention is a method for treating a patient suffering from addiction, including identifying a patient in need of treatment and administering said composition to the patient.
EFFECT: compositions and methods for treating addiction, mental disorders and neurodegenerative disease are disclosed.
5 cl, 5 ex
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Authors
Dates
2018-12-06—Published
2011-06-16—Filed