FIELD: medicine; pharmaceutics.
SUBSTANCE: invention refers to medicine and pharmaceutics. Dry granulated pharmaceutical formulation containing atorvastatin or its pharmaceutically acceptable salt, in combination with at least one other active medicinal agent, method of specified formulations production, sets including such formulations, and treatment of hypercholesterolemia and/or hyperlipidemia, osteoporosis, benign prostate hyperplasia (BPG) and Alzheimer's disease by using pharmaceutical formulation in amount providing therapeutic effectiveness. Offered pharmaceutical formulation of atorvastatin is characterised with good solubility, bioavailability, dosage homogeneity, and method of atorvastatin production with low content of impurities and adequate stability.
EFFECT: production of atorvastatin formulation, characterised with good solubility, bioavailability, dosage homogeneity, and method of atorvastatin production with low content of impurities and adequate stability.
6 cl, 6 ex, 5 tbl
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