CRYSTALLINE FORMS OF KNOWN PYRROLIDINE INHIBITOR OF XA FACTOR Russian patent published in 2009 - IPC C07D401/12 A61K31/513 A61P7/02 

Abstract RU 2368610 C2

FIELD: chemistry.

SUBSTANCE: invention relates to crystalline forms of 1,2-pyrrolidinedicarboxamide, N1-(4-chlorophenyl)-N2-[2-fluoro-4-(2-oxo-1(2H)-pyridinyl)phenyl]-4-methoxy-, (2R,4R)-(9CI), as well as to methods of obtaining said crystalline forms and to their pharmaceutical compositions, which have inhibitory activity towards Xa factor.

EFFECT: high stability of new crystalline forms.

19 cl, 9 ex, 7 dwg, 5 tbl

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RU 2 368 610 C2

Authors

Samas Brajan Mehtt'Ju

Vriz Derek Klinton

Dates

2009-09-27Published

2006-03-13Filed