METHOD OF SYSTEMIC FAT EMBOLISM DEVELOPMENT PREVENTION IN PERIOPERATIVE PERIOD Russian patent published in 2008 - IPC A61K31/7004 A61K31/197 A61K31/4415 A61K31/47 A61K31/455 A61K31/525 A61K33/14 A61P41/00 G01N33/38 

FIELD: medicine.

SUBSTANCE: hepasol A in dosage 4.0-8.0 ml/kg and 5% glucose solution are injected separately in equal dosages 40 minutes before surgery. After main operation step is complete blood is microscopically tested for fat globules. In case 10 globules of size less than 5 mcm, or one or more globules of size more than 5 mcm are found totally within 8 microscopic field, test result is considered to be positive, and Hepasol A and 5% glucose solution introduction is prolonged. In case no globules found or those found are totally less than 10 in number of size less 5 mcm test result is considered to be negative, thus Hepasol A and 5% glucose solution introduction is stopped. Blood is repeatedly tested for fat globules in 12 hours after last introduction of Hepasol A. If positive test result for fat globules is registered, Hepasol A and 5% glucose solution introduction is recommenced, and in case double negative test result is registered, Hepasol A is not introduced.

EFFECT: method allows preventing of systemic fat embolism development in perioperative period.

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