METHOD OF TREATING OPERABLE PANCREATIC HEAD ADENOCARCINOMA Russian patent published in 2019 - IPC A61K31/513 A61K31/506 A61K31/555 A61P35/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine and aims at treating operable pancreatic adenocarcinoma (AP). Method involves intra-arterial infusion introduction of 50 mg/m² oxaliplatin through catheter into gastroduodenal artery for 20 minutes, then bolus suspension 50 mg/m² Abraxane in no more than 5 ml of Lipiodol, after which the catheter is reinserted into the celiac and intra-arterially infusion 1,000 mg/m² gemcitabine for one hour, followed by surgical removal of tumor, after which no earlier than 2 weeks later, infusion gemcitabine is introduced into a celiac stem in amount of 1,000 mg/m² followed by systemic chemotherapy by oral administration of capecitabine daily at 2,500 mg/m² per day in 2 divided doses in the morning and in the evening for no more than 14 days, not more often 1 time a month before occurrence of undesirable phenomena of II-III degree or progression of tumor process by criteria RECIST.

EFFECT: method provides higher therapeutic tolerance.

1 cl, 1 ex