FIELD: medicine; pharmacology.
SUBSTANCE: medicinal agent is mixed with preaerated and irradiated with accelerated electron current or pulse UV-laser radiation 5.0-50.0% polyethylene oxide solution of molecular weight 0.4-20 kilodaltons in presence of 0.01-0.1 M phosphate buffer, pH 6.0-8.0 and containing 0.05-0.3 M sodium chloride. Offered method is easy and multipurpose, and can be applied to increase enteral bioavailability of medicinal agents introduced mainly or solely parenterally due to low resorption by intestine walls.
EFFECT: increased enteral bioavailability of medicinal agents.
4 cl, 3 tbl, 10 ex, 1 dwg
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