MEDICAL PRODUCT AND METHOD OF RHEUMATIC DISEASES TREATMENT Russian patent published in 2008 - IPC A61K31/519 A61K47/44 A61K9/127 A61P19/02 A61P19/00 

Abstract RU 2330664 C2

FIELD: medicine; rheumatology.

SUBSTANCE: preparation includes 0.1-3.0 mass % of methotrexate within phospholipid nanoparticles. Nanoparticles consist of phospholipids, glycyrrhizic acid or its salt and adjuvants. The total content of phospholipids and glycyrrhizic acid and its salts is 2-80 mass %. Mass ratio of phospholipids and glycyrrhizic acid or its salts is no more 4:1. Invention also concerns method of rheumatic diseases treatment by means of specified preparation.

EFFECT: decrease in preparation by-effects and maintenance of its therapeutic potential for rheumatic diseases treatment.

4 cl, 3 dwg, 1 tbl, 1 ex

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RU 2 330 664 C2

Authors

Archakov Aleksandr Ivanovich

Guseva Marija Kirillovna

Ipatova Ol'Ga Mikhajlovna

Tikhonova Elena Georgievna

Zykova Marija Gennadievna

Nasonov Evgenij L'Vovich

Korotaeva Tat'Jana Viktorovna

Prozorovskij Vladimir Nikolaevich

Dates

2008-08-10Published

2006-04-26Filed