NANOFORM OF PHOSPHOLIPID PREPARATION FOR ORAL APPLICATION AND METHOD FOR MAKING THEREOF Russian patent published in 2009 - IPC A61K9/127 A61K31/685 A61P1/16 B82B1/00 

FIELD: medicine.

SUBSTANCE: invention relates to pharmaceutics and medicine and concerns an oral medicinal form of a phospholipid preparation for prevention and treatment of hepatopathy, lipid storage disease and hepatic function recovery following intoxication, in the form of nanoparticles of diametre 30-50 nm, containing vegetable phospholipids with phosphatidyl choline content 75-98%, glycyrrhizic acid or its pharmaceutically acceptable salt and a carbohydrate with the total content of phospholipids and glycyrrhizic acid or its pharmaceutically acceptable salt 2-80 wt % and mass ratio of phospholipids to glycyrrhizic acid or its pharmaceutically acceptable salt 4:1 or less, as well as method for making thereof by mixture emulsion of vegetable phospholipids in aqueous solution of glycyrrhizic acid or its pharmaceutically acceptable salt with aqueous solution of carbohydrates at pH 6.5-7.5, then followed with homogenisation at pressure 800-1200 bar and sublimation drying.

EFFECT: there is developed oral medicinal form of the phospholipid preparation for prevention and treatment of hepatopathy, lipid storage disease and hepatic function recovery following intoxication.

3 cl, 1 ex, 3 dwg