CHROMATOGRAPHIC METHOD OF EREMOMYCIN PURIFICATION Russian patent published in 2008 - IPC C12P21/00 C12P1/06 B01D15/42 

Abstract RU 2333963 C1

FIELD: chemistry.

SUBSTANCE: invention relates to technology of glycopeptides purification. Clarified liquid containing eremomycin is compacted with sulphuretted stirol-divinylbenzene cationite, elution is carried out and neutralised eluate is applied on the column with hydrophobic stirol divinylbenzene sorbent. After washing column with water, eremomycin is displaced with solution of isopropyl alcohol with addition of acetic acid and crystallisation of target product is carried out.

EFFECT: obtaining a pure product with a high output at a high process productivity.

6 cl, 3 ex

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RU 2 333 963 C1

Authors

Karasev Viktor Semenovich

Katrukha Genrikh Stepanovich

Staroverov Sergej Mikhajlovich

Zharov Oleg Vladimirovich

Dates

2008-09-20Published

2006-11-21Filed