METHOD OF CORRECTION OF DISORDERS PEROXIDE OXIDATION OF LIPIDS AND ANTIOXIDATIC ACTIVITY AT STRESS-REACTION AFTER SURGERY OPERATIONS ON THYROID GLAND Russian patent published in 2008 - IPC G01N33/92 A61K31/44 

FIELD: medicine.

SUBSTANCE: invention is referred to medicine area, namely to surgery and intensive care, and can be used for treatment of disorders of peroxide oxidation (POX) and antioxidatic activity (AOA) at patients at stress-reaction after operations on a thyroid gland. The method provides early correction of postoperative disorders of POX and AOA (in an hour after an operation). Define indicators of peroxide oxidation of lipids - diethenoid conjugates and hydroperoxides of lipids and antioxidatic activity of plasma - a hepatocuprein in blood serum of patients 1 hour prior to operation and in 1 hour after operation and at rising of the content of products POX in 1 hour after operation in 1.5 times and more, and also hepatocuprein depression in 1.5 times and more in comparison with preoperational level, perform medicamental correction by the continued intravenous infusion of 1% emoxipine solution of 20 ml with a dosing syringe with rate of 0.1-0.15 mg/minutes within 24 hours, in 24 hours after operation and after the emoxipine infusion termination perform control analyses for an effect estimation of antioxidant therapy and in the event that POX indicators are above initial level in 1.5 times, AOA below initial level in 1.5 times, repeat emoxipine infusion within next days in the same dose.

EFFECT: provision of early correction of postoperative disturbances of POX and AOA.

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