FIELD: chemistry.
SUBSTANCE: invention pertains to new derivatives of 2-pyridinecarboxamide and their pharmaceutical salts, which have glucokinase activating properties. In formula (I): 
D represents O or S; R2 and R3 each represents a hydrogen atom; formula (II) 
represents triazole group, imidazole group, thiazole group and pyridine group, which can have in the ring, 1 or 2 substitutes; formula (III) 
represents a thiazole group, thiadiazole group, isoxazolyl group, pyrazine group, pyridothiazolyl group or pyridyl group, ring B can have 1 or 2 substitutes. The invention also relates to pharmaceutical compositions based on the invented compounds.
EFFECT: new derivatives can be used for treating such diseases as sugar diabetes.
19 cl, 5 tbl, 165 ex
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