AGONISM OF 5НТ-RECEPTOR FOR TREATMENT OF DISTURBANCE OF THERMOREGULATION FUNCTION Russian patent published in 2008 - IPC A61K31/138 A61K31/4525 A61K31/135 A61K31/15 A61K31/553 A61K31/343 A61K31/55 A61K31/381 A61K31/496 A61K31/166 A61P15/12 A61P5/00 A61K45/00 

Abstract RU 2340333 C2

FIELD: medicine; pharmacology.

SUBSTANCE: combined preparation includes an inhibitor of repeated absorption of the serotonin, representing fluoxetine, and the antagonist of a 5NT1a-receptor chosen from group, which make N-[2[4(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinilcyclohexancarboxamide and (R)-N-(2-methyl-(4-indolil-1-piperazinyl)ethyl)-N-(2-pyridinil) cyclohexancarboxamide, in therapeutically effective amounts.

EFFECT: treatment of thermoregulation function disorders at patients that cannot be exposed to ways of medical influence on the basis of steroids.

2 cl, 5 ex, 5 dwg

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Authors

Dicher Darlin Koulman

Merchentehjler Ishtvan Jozef

Levental' Liza

Sajp Kimberli Dzhin

O`Konnor Lorens Tomas

Andri Terrans Kharol'D

Dates

2008-12-10Published

2003-08-14Filed