FIELD: medicine.
SUBSTANCE: invention relates to a method for treating or preventing vasomotor symptoms in women, such as hot flashes and sweating, involving introduction of 50 mg per day of an antagonist of melastatin-8 with transient receptor potential (TRPM8), constituting 4-({(4-cyclopropylisoquinoline-3-yl)[4-(trifluoromethoxy)benzyl]amino}sulphonyl)benzoic acid, as well as an application of the TRPM8 antagonist constituting 4-({(4-cyclopropylisoquinoline-3-yl)[4-(trifluoromethoxy)benzyl]amino}sulphonyl)benzoic acid, for treating or preventing vasomotor symptoms.
EFFECT: treatment of vasomotor symptoms in women by introducing 4-({(4-cyclopropylisoquinoline-3-yl)[4-(trifluoromethoxy)benzyl]amino}sulphonyl)benzoic acid at a dose of 50 mg per day.
13 cl, 4 dwg, 1 tbl, 2 ex
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