COMPOSITIONS AND METHODS OF TREATMENT OR PREVENTION OF VASOMOTOR SYMPTOMS Russian patent published in 2024 - IPC A61K31/47 A61K31/42 A61K31/425 A61K31/445 A61P9/14 

Abstract RU 2815402 C2

FIELD: medicine; therapy; endocrinology.

SUBSTANCE: group of inventions is intended for the treatment or prevention of vasomotor symptoms. The following is used: 4-({(4-cyclopropylisoquinolin-3-yl)[4-(trifluoromethoxy)benzyl]amino}sulfonyl)benzoic acid or a pharmaceutically acceptable salt thereof or a composition containing the same as an agent for treating or preventing vasomotor symptoms in a subject in need of it. Also the following is provided: a method of treating or preventing vasomotor symptoms in a subject in need thereof, a method comprising administering to the subject 4-({(4-cyclopropylisoquinolin-3-yl)[4-(trifluoromethoxy)benzyl]amino}sulfonyl)benzoic acid or a pharmaceutically acceptable salt thereof in a daily dose of 10 mg or less.

EFFECT: use of the group of inventions makes it possible to increase the effectiveness of the treatment or prevention of vasomotor symptoms.

26 cl, 7 dwg, 2 tbl, 2 ex

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RU 2 815 402 C2

Authors

Palumbo, Joseph M.

Dates

2024-03-14Published

2018-12-18Filed