STENTS WITH COATING CONTAINING N-{5-[4-(4-METHYLPIPERAZINOMETHYL)BENZOYL-AMIDO]-2-METHYLPHENYL}-4-(3-PYRIDYL)-2-PYRIMIDINAMIN Russian patent published in 2008 - IPC A61K31/501 A61K31/496 A61L29/16 A61L31/16 A61F2/06 A61P9/10 

Abstract RU 2341266 C2

FIELD: medicine.

SUBSTANCE: offered is medical device adapted for local application or introduction in hollow tubes and containing therapeutic dose of N-{5-[4-(4-methylpiperazinomethyl) benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidinamine or its salt, crystal form with possible release thereof, its application for prevention or reduction of dysfunction caused by approach to vessels and related method of treatment (prevention). Particularly offered is method of restenosis treatment or prevention inpatients suffering from diabetes. It is detected that local introduction of M-{5-[4-(4-methylpiperazinomethyl) benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidinamine or its pharmaceutically acceptable salt or crystal form under declared method provides unexpectedly high stability of compound within 45 days compared to its activity value when introduced as free form.

EFFECT: provides high stability of compound.

5 cl, 7 ex

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RU 2 341 266 C2

Authors

Preskott Margaret Forni

Feldman Dejvid Luis

Dates

2008-12-20Published

2003-02-27Filed