METHOD OF PREVENTION OR TREATMENT OF REDUCTION OF ACCESS FOR VESSEL HEMODIALYSIS AND DEVICE FOR ITS REALISATION AND OTHER VASCULAR GRAFTS Russian patent published in 2009 - IPC A61B17/00 A61K31/727 A61K38/39 A61P7/02 

FIELD: medicine.

SUBSTANCE: essence of claimed inventions lies in local extravascular introduction of vasculoproliferative compound of rapamicyn, which is carried out by means of device, placed on outer vessel surface. Device represents implanted cuff containing flexible matrix material in form of cylindrical tube, which has opening, corresponding to vessel size. Matrix material contains dispersed in it antiproliferative agent - rapamicyn, which being gradually released from cuff, locally goes into vessel wall.

EFFECT: efficient reduction or prevention of vascular proliferation and hyperplasia of unstriped muscle cells due to prolonged supply of constant concentration of rapamicyn locally into vessel wall.

36 cl, 12 tbl, 14 ex, 20 dwg