FIELD: medicine; pharmacology.
SUBSTANCE: production of new chemical compounds hypoglycemic effect, namely new complex compound of oxovanadium (IV) with glycine. Method of production and release of crystal complex compound of oxovanadium (IV) with glycine of hypoglycemic action is described. Composition of complex compound of vanadyl with glycine at ratio vanadyl:glycine: sulphate as 1:2:1 is experimentally proved. Analysis of acute toxicity of complex compound of vanadyl with glycine shows that produced complex concerns medium toxic compounds and is less toxic than vanadyl sulphate.
EFFECT: high hypoglycemic activity of produced complex compound of vanadyl with glycine.
1 cl, 3 ex, 3 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| NOVEL CHELATE COMPOUND OF OXOVANADIUM (IV) WITH ISONICOTINIC ACID HYDRAZIDE SHOWING ANTIDIABETIC ACTION AND ELICITING ANTIMYCOBACTERIAL ACTIVITY | 1999 |
|
RU2190618C2 |
| OXOVANADIUM COMPLEXES OF L-MALIC ACID SHOWING HYPOGLYCEMIC ACTIVITY | 1996 |
|
RU2101287C1 |
| OXOVANADIUM (IV) COMPLEX IN DIMETHYL SULPHOXIDE POSSESSING ANTIDIABETIC ACTION AND METHOD FOR PRODUCING IT | 2014 |
|
RU2559894C1 |
| BIS[3-(4-CHLOROPHENYL)-1-(4-METHYLPHENYL)CARBOXAMIDO-1,3-PROPANEDIONATO]OXOVANADIUM, HAVING HYPOGLYCEMIC AND ANTIHYPOXIC ACTIVITY | 2010 |
|
RU2432355C2 |
| NOVEL VANADIUM DERIVATIVES HAVING HYPOGLYCEMIC ACTIVITY | 2019 |
|
RU2709491C1 |
| BIOLOGICALLY ACTIVE NUTRITIVE SUPPLEMENT WITH INSULIN-LIKE EFFECT BASED ON BIS-(L-MALATO)-OXOVANADIUM (IV) | 2000 |
|
RU2191018C2 |
| ANTIDIABETIC AGENT | 1998 |
|
RU2150952C1 |
| PHARMACEUTICAL COMPOSITION WITH ANTIDIABETIC EFFECT BASED ON OXOVANADIUM DERIVATIVE AND METHOD FOR IT PREPARING | 2001 |
|
RU2203656C1 |
| N-(4-CHLORBENZENE)SULFONYL -N - [7-(1,3,5 -TRIAZADAMINTYL) CARBAMIDE POSSESSING HYPOGLYCEMIA ACTIVITY | 1984 |
|
SU1254698A1 |
| BIS- (3- (3,5-DI-TERT-BUTYL-4-HYDROXYPHENYL) PROPYL) SELENIDE, HAVING ANTIOXIDANT AND HYPOGLYCEMIC ACTIVITY | 2015 |
|
RU2586067C1 |
