ANHYDROUS, FREE FROM ETHYL ALCOHOL, INCLUDING ASCOMYCINE COMPOSITIONS FOR LOCAL APPLICATION Russian patent published in 2009 - IPC A61K31/4353 A61K47/10 A61K47/14 A61K47/26 A61K47/44 A61K47/36 A61K9/08 A61K9/06 A61P17/00 A61P37/00 

FIELD: medicine; pharmacology.

SUBSTANCE: semifirm pharmaceutical compositions for local application include ascomycene in solution of carrier including three-componental admixture of dissolvents, component not less than 40% wt from lump of composition and consisting from: i) C_3-8-alkanol and-or C_1-8-alkandiol; ii) fat alcohol iii) additional dissolvents chosen from the family, containing:) alkyl ether of alkancarboxylic acid and-or alkyl ether alkandincarboxylic acid and-or a hydrophylic additional component and-or a triglyceride. Besides, the invention concerns application of the specified composition and the method of treatment of inflammatory and hyperproliferative diseases of skin and dermal implications of immunologically mediated diseases.

EFFECT: improvement of penetration of active substance.

9 cl, 7 tbl, 26 ex