PIMECROLIMUS FOAMY COMPOSITION INCLUDING HEXYLENE GLYCOL, OPTIONALLY OLEYL ALKOHOL AND/OR MEDIUM CHAIN TRIGLYCERIDES Russian patent published in 2009 - IPC A61K9/12 A61K47/10 A61P17/00 A61K31/453 

Abstract RU 2375044 C2

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to pharmaceutical foamy compositions, virtually ethanol-free and including pimecrolimus in carrier-base, containing mixture of oily solvents, which constitutes at least up to 40% of total composition weight and includes: I) hexylene glycol; II) optionally oleyl alcohol and III) dimethylisosorbide and/or medium chain triglycerides; IV) in absence of oleyl alcohol, less than 10 % of water; V) at least one consistency-forming additive; VI) preservative; VII) at least one surface-active substance-emulsifier and VIII) propellant gas for foaming.

EFFECT: such compositions are indicated for application in treatment of various skin diseases, nail diseases and mucous tunic.

5 cl, 3 ex

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RU 2 375 044 C2

Authors

Ehjni Mejr

Fridman Doron

Khirsh Shtefan

Mejenburg Zabine

Sekkat Nabila

Tamarkin Dov

Dates

2009-12-10Published

2005-04-07Filed