OXAZOLES AS mGluR1 AMPLIFIERS Russian patent published in 2009 - IPC C07D413/12 A61K31/422 A61K31/352 A61P25/00 

Abstract RU 2345076 C2

FIELD: chemistry, pharmaceutics.

SUBSTANCE: claimed invention relates to novel compounds of formula (I) and their pharmaceutically acceptable salts. Compounds of claimed invention possess properties of agonists of mGlu 1 receptors and can find application in treatment of such diseases as psychosis, schizophrenia, Alzheimer's disease, etc. In general formula (I) one of R1 and R2 stands for trifluoromethyl, the other stands for hydrogen; R3, R3' independently on each other stand for hydrogen or halogen.

EFFECT: obtaining medication which possesses properties of agonists of mGlu 1 receptors.

7 cl, 2 tbl, 2 dwg, 17 ex

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RU 2 345 076 C2

Authors

Khuviler Jerg

Knoflakh Frederik

Viajra Ehrik

Vikhmann Jurgen

Dates

2009-01-27Published

2003-12-17Filed