MINIMAL FLOW INHALATIONAL ANESTHESIA METHOD Russian patent published in 2009 - IPC A61K31/4402 A61K31/46 A61K31/4468 A61K31/05 A61K31/4425 A61K31/02 A61K33/14 A61P23/00 A61M16/01 A61B17/00 

FIELD: medicine; traumatology and orthopaedics.

SUBSTANCE: minimal flow anaesthesia based on application of Sevoflurane and fast restoration recovery of vital functions within near-term postoperative period includes as followed. Minimal flow inhalation anaesthesia 0.5 l/min is based on application of Sevoflurane of MAC 0.5-1.0 in oxygen-air mixture. Anaesthesia is deepened with Suprastine premedication in dosage 0.25 mg/kg. 15 minutes prior to be induced to anaesthesia, Ringer's solution is intravenously injected in dosage 7-8 ml/kg. For initial narcosis, Atropine dosed 0.012 mg/kg and Fentanyl dosed 1.32 mkg/kg are used. Induction is represented with Propovan 1% introduction in dosage 2.6-3.2 mg/kg followed with Esmeron dosed 0.65 mg/kg. After myoplegia is ensued in 90 seconds, laryngoscopy and intubation of trachea follow. Myoplegia is maintained with infused Esmeron dosed 0.26-0.37 mg/kg/h. Artificial pulmonary ventilation is carried out through endotracheal tube in IPPV reverse-circuit mode with respiratory volume 7-8 ml/kg and respiratory minute volume 80-90 ml/kg, FiO₂=35-40% with controlled SpO₂ and EtCO₂. High-calcium lime is used as a sorbent. Spondylosyndesis operation in open pneumothorax at pneumothorax application stage implies infusion of balanced potassium magnesium aspartate in amount 3-3.5 ml/kg. 2 minutes prior to collaber lung is straightened, anaesthesia is deepened by Fentanyl introduction in dosage 1.25-1.5 mkg/kg. Additionally Ingitril 30 UNITS is introduced to the patients suffering from complicated spine injury.

EFFECT: managed adequate anaesthetic protection with minimal pharmacological effect on patient's homeostasis.

4 cl, 2 ex