FIELD: chemistry.
SUBSTANCE: present invention pertains to new cycloalkylidene compounds with formula (I), to their pharmaceutical salts, esters and amide, capable of selective bonding ERα- and ERβ-estrogen receptors, as well as to pharmaceutical compositions based on them, their use in making medicinal preparations and the method of selective bonding ERα- and ERβ-estrogen receptors. 
. Denotations of R1-R7, X, p, q, as well as specific representatives of new cycloalkylidene compounds are given in the formula of invention.
EFFECT: obtaining new cylcoalkylidene compounds.
31 cl, 6 dwg, 108 ex
| Title |
Year |
Author |
Number |
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|
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|
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|
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|
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