CHEMICAL COMPOUNDS, PHARMACEUTICAL CMPOSITION, CONTAINING THEM, THEIR APPLICATION (VERSIONS) AND METHOD OF BINDING ERα AND ERβ -ESTROGEN RECEPTORS Russian patent published in 2009 - IPC C07C65/24 C07C59/66 C07D211/62 C07D295/104 C07D333/24 C07D307/56 C07D213/55 C07D207/12 C07C255/54 C07C311/08 C07C311/09 C07C235/34 C07F9/38 A61K31/216 A61K31/235 A61P5/30 

FIELD: chemistry.

SUBSTANCE: invention relates to novel compounds of formula (I), including its pharmaceutically acceptable salts, solvates, ethers and amides, possessing ability to bind ERα- and ERβ-estrogen receptors, to pharmaceutical composition based on them, to versions of applying claimed compounds in medication preparation and to method of binding ERα- and ERβ-estrogen receptors. (I), where R¹ represents H, OH or C_1-12alkoxy, or halogen; R² represents H, OH or halogen; R³ represents C_1-12alkyl, halogeno-C_1-12alkyl, C_3-10cycloalkyl, C_1-12alkoxy or C_1-12alkoxyC_1-12alkyl; R⁴ represents H or C_1-12alkoxy; R⁵ represents H, halogen or halogeno-C_1-12alkyl; R⁶ represents -(Y)_z-R⁷; R⁸ represents phenyl or 5- or 6-member heteroaryl, containing N, O or S as heteroatom, where said phenyl and heteroaryl are possibly substituted with OH, halogeno, halogenoC_1-12alkyl or C_1-12alkoxy. Values R⁷, Y and z are presented in invention formula.

EFFECT: novel compounds possess useful biological properties.

19 cl, 7 dwg, 1 tbl, 70 ex