METALLOPROTEINASE-9 OLIGOPEPTIDES AND THEIR THERAPEUTIC USE Russian patent published in 2017 - IPC A61K39/00 C12N9/64 A61P35/00 

Abstract RU 2628702 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to a composition for treatment of a disease and methods for treatment of a disease accompanied by increased expression of MMP-9 matrix metalloproteinase. Oligopeptides with SEQ ID NO: 7, 11, 12, 18 or 19 are used to prepare the composition. These oligopeptides bind to antibodies to generate an immune response in a mammalian subject against MMP-9 matrix metalloproteinase.

EFFECT: invention allows to increase the efficiency of blocking of extracellular matrix cleavage by MMP-9 metalloproteinase molecules and to increase the efficiency of oncological and other diseases treatment.

16 cl, 14 dwg, 8 tbl

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RU 2 628 702 C2

Authors

Rat Matias

Nidzvitski Aleksandra

Rumi Vakhid M.

Dates

2017-08-21Published

2013-04-10Filed