16-{2-BENZOYLAMINO-2-[(3,5-DI-TRET-BUTHYL-4-HYDROXUPHENYL)ALKYL-CARBAMOYL]VINYL}-LABDATRIENS WITH ANTIOXIDANT, HEPATOPROTECTION AND HEMOSTIMULATING EFFECT Russian patent published in 2009 - IPC C07D307/52 A61K31/341 A61P1/16 

Abstract RU 2346940 C1

FIELD: chemistry.

SUBSTANCE: invention concerns new compounds, particularly 16-{2-benzoylamino-2- [(3,5-di-tet-buthyl-4-hydroxyphenyl)-alkylcarbamoyl]vinyl}-labdatriens of the formula (I) with antioxidant, hepatoprotection and hemostimulating effect, allowing for application under toxic hepatitis and in correction of side effects of cytostatic medicines (e.g. cyclophosphane). Compounds of the formula 1 are obtained from raw plant material, Siberian cedar needles or oleo-resin.

EFFECT: obtaining compounds with antioxidant, hepatoprotection and hemostimulating effect.

4 tbl, 5 ex

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RU 2 346 940 C1

Authors

Kharitonov Jurij Viktorovich

Shul'Ts Ehl'Vira Ehduardovna

Sorokina Irina Vasil'Evna

Tolstikova Tat'Jana Genrikhovna

Baev Dmitrij Sergeevich

Zhukova Natal'Ja Anatol'Evna

Tolstikov Genrikh Aleksandrovich

Dates

2009-02-20Published

2007-08-23Filed