FIELD: chemistry.
SUBSTANCE: invention concerns new compounds, particularly 16-{2-benzoylamino-2- [(3,5-di-tet-buthyl-4-hydroxyphenyl)-alkylcarbamoyl]vinyl}-labdatriens of the formula (I) with antioxidant, hepatoprotection and hemostimulating effect, allowing for application under toxic hepatitis and in correction of side effects of cytostatic medicines (e.g. cyclophosphane). Compounds of the formula 1 are obtained from raw plant material, Siberian cedar needles or oleo-resin.
EFFECT: obtaining compounds with antioxidant, hepatoprotection and hemostimulating effect.
4 tbl, 5 ex
Title | Year | Author | Number |
---|---|---|---|
(Z)-METHYL-16-(5-OXO-2-PHENYL-OXAZOL-4-ILIDENMETHYL)-15,16-EPOXY-8(17),13(16),14-LABDATRIEN-18-OATE, POSSESSING ANTIOXIDATIVE, HEPATOPROTECTIVE AND HEMOSTIMULATING ACTIVITY | 2007 |
|
RU2353620C1 |
ANTIOXIDANT, POSSESSING HEPATOPROTECTIVE AND HEMOSTIMULATING ACTIVITY | 2007 |
|
RU2364599C2 |
BENZYLURSONATE - ANTI-INFLAMMATORY AND HEPATOPROTECTIVE AGENT | 2010 |
|
RU2430106C1 |
AGENT HAVING ANTIOXIDANT, HEPATOPROTECTOR AND ANTI-INFLAMMATORY PROPERTIES | 2010 |
|
RU2436793C1 |
POTASSIUM SALT OF CARBOXYMETHYL ESTER OF 3-OXY-URSAN-12-ENE-28 ACIDS EXHIBITING HEPATOPROTECTIVE, ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITY | 2010 |
|
RU2430105C1 |
(3aR, 4aS, 6aR, 9aR, E)-3-ARYLIDEN-8a-METHYL-5-METHYLENE-DECAHYDRONAPHTO [2,3-b]FURAN-2(3H)-ONES, POSSESSING ANTI-ULCER ACTIVITY | 2009 |
|
RU2413724C1 |
N-SUBSTITUTED (1S,4AR,5S)-METHYL-5-[2-(2'-OXO-2',5'-DIHYDRO1-H-PYRROL-3'-YL)ETHYL]-1,4A-DIMETHYL-6-METHYLENEDECAHYDRONAPHTHALENE-1-CARBOXYLATES HAVING ANTICONVULSANT ACTIVITY | 2008 |
|
RU2385863C2 |
AGENT FOR CORRECTION OF CYTOSTATIC POLYCHEMOTHERAPY WITH ANTI-INFLAMMATORY ACTIVITY | 2010 |
|
RU2425680C1 |
NEW COMPLEX OF BIOLOGICALLY ACTIVE COMPOUNDS OUT OF LARCH BARK NAMED PICNOLAR | 2003 |
|
RU2252028C2 |
16-(1,2,4-OXADIAZOL-3-YL)-15,16-EPOXILABDANOIDS POSSESSING CYTOTOXIC ACTIVITY ON HUMAN TUMOUR CELLS | 2011 |
|
RU2473550C1 |
Authors
Dates
2009-02-20—Published
2007-08-23—Filed