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2 353 620

(13)

(51)

IPC

C07D413/06(2006-01-01)

A61K31/421(2006-01-01)

A61P39/06(2006-01-01)

A61P1/16(2006-01-01)

A61P7/00(2006-01-01)

(21) (22)

Application

2007132037/04, 2007-08-23

(24)

Start date

2007-08-23

(22)

Actual filing date

2007-08-23

(45)

Published

2009-04-27

(72)

Inventor

Kharitonov Jurij ViktorovichShul'Ts Ehl'Vira EhduardovnaSorokina Irina Vasil'EvnaTolstikova Tat'Jana GenrikhovnaBaev Dmitrij SergeevichZhukova Natal'Ja Anatol'EvnaTolstikov Genrikh Aleksandrovich

(73)

Holder

Novosibirskij Institut Organicheskoj Khimii Im. N.N. Vorozhtsova So Ran So Ran)

(Z)-METHYL-16-(5-OXO-2-PHENYL-OXAZOL-4-ILIDENMETHYL)-15,16-EPOXY-8(17),13(16),14-LABDATRIEN-18-OATE, POSSESSING ANTIOXIDATIVE, HEPATOPROTECTIVE AND HEMOSTIMULATING ACTIVITY Russian patent published in 2009 - IPC C07D413/06 A61K31/421 A61P39/06 A61P1/16 A61P7/00

Abstract RU 2353620 C1

FIELD: chemistry.

SUBSTANCE: invention relates to (Z)-methyl-16-(5-oxo-2-phenyl-oxazol-4-ilidenmethyl)-15,16-epoxy-8(17),13(16),14-labdatrien-18-oate of formula (I) (I). Compound (I) possesses high antioxidative, hepatoprotective and hemostimulatng activity and can be used for correction of side effects, arising with introduction of highly toxic medications used in anti-tumor therapy.

EFFECT: obtaining compound, which possesses high antioxidative, hepatoprotective and hemostimulatng activity.

1 cl, 4 tbl, 4 ex

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RU 2 353 620 C1

Authors

Kharitonov Jurij Viktorovich

Shul'Ts Ehl'Vira Ehduardovna

Sorokina Irina Vasil'Evna

Tolstikova Tat'Jana Genrikhovna

Baev Dmitrij Sergeevich

Zhukova Natal'Ja Anatol'Evna

Tolstikov Genrikh Aleksandrovich

Dates

2009-04-27—Published

2007-08-23—Filed