FIELD: medicine; oncology.
SUBSTANCE: induction chemotherapy is carried out by introduction of cisplatin and 5-fluorouracyl. Then chemoradiation therapy is performed with introduction of carboplatin once a week. Thirty-forty minutes before performance of radiation therapy, "Coletex-gel-DNA-L" is introduced into patient's oral cavity. Introduction of "Coletex-gel-DNA-L" is continued every 3-4 hours during radiation therapy and 2-3 times per day for 1 month on its completion. Patient's radiation is carried out daily until total focal dose makes 72-74 Gy with application of conformal radiation therapy on the basis of volume three-dimensional planning.
EFFECT: maximum safe radiation therapy with significant reduction of local toxic reaction of organism.
2 ex
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Authors
Dates
2009-02-27—Published
2007-11-02—Filed