Show metadata Hide metadata

(19)

(11)

2 348 613

(13)

(51)

IPC

C07C251/86(2006-01-01)

A61P29/00(2006-01-01)

A61K31/15(2006-01-01)

(21) (22)

Application

2006144008/04, 2006-12-11

(24)

Start date

2006-12-11

(22)

Actual filing date

2006-12-11

(45)

Published

2009-03-10

(72)

Inventor

Pulina Natal'Ja AlekseevnaZalesov Vladimir Vasil'EvichBystritskaja Oksana Anatol'EvnaJushkov Vladimir ViktorovichJatsenko Konstantin Vjacheslavovich

(73)

Holder

Gosudarstvennoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennaja Farmatsevticheskaja Akademija Federal'Nogo Agentstva Po Zdravookhraneniju I Sotsial'Nomu Razvitiju" Vpo Pgfa Roszdrava)

2-(1,2-DIPHENYL-2-OXOETHYLIDENEHYDRAZINO)-4-(4-METHOXYPHENYL)-4-OXOBUT-2-ENE ACID WITH ANTI-INFLAMMATORY AND ANALGESIC EFFECT Russian patent published in 2009 - IPC C07C251/86 A61P29/00 A61K31/15

Abstract RU 2348613 C2

FIELD: chemistry.

SUBSTANCE: invention concerns new bioactive compound of 4-aryl-2,4dioxybutane acid class, - 2-(1,2-diphenyl-2-oxoethylidenehydrazino)-4-(4-methoxyphenyl)-4-oxobut-2-ene acid of the formula (I) .

EFFECT: anti-inflammatory and analgesic effect, low toxicity.

1 ex, 1 tbl

Similar patents RU2348613C2

Title	Year	Author	Number
4-(4-METHYLPHENYL)-4-OXO-2-[3-(ETHOXYCARBONYL-4,5-R,R-THIOPHEN-2-YLAMINO]BUT-2-ENOIC ACID, HAVING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY	2008	Shipilovskikh Sergej Aleksandrovich Rubtsov Aleksandr Evgen'Evich Makhmudov Ramiz Ragipovich Zalesov Vladimir Vasil'Evich	RU2389724C1
4-(4-BROMOPHENYL)-4-OXO-2-{[3-ETHOXYCARBONYL)-4,5-DIMETHYLTHIEN-2-YL]AMINO}-2-BUTENOIC ACID, HAVING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY	2012	Makhmudov Ramiz Ragibovich Rubtsov Aleksandr Evgen'Evich Shipilovskikh Sergej Aleksandrovich	RU2485112C1
APPLICATION OF 4-ARYL-4-OXO-2-[2-(9H-FLUORENE-9-YLIDENE)HYDRAZONO] BUT-2-ENO ACIDS AS ANALGESICS	2021	Rubtsov Aleksandr Evgenevich Makhmudov Ramiz Ragibovich	RU2771030C1
BIS{3-PHENYL-1-[N-(3-PYRIDYL)CARBOXAMIDO]-1,3-PROPANDIONATO} CADMIUM, WHICH HAS ANTI-FLAMMATORY ACTIVITY	2007	Pulina Natal'Ja Alekseevna Jushkov Vladimir Viktorovich Mokin Pavel Aleksandrovich Zalesov Vladimir Vasil'Evich Jatsenko Konstantin Vjacheslavovich	RU2342364C1
(Z)-2-[(3-CARBAMOYL-4,5,6,7-TETRAHYDROBENZO[b]THIEN-2-YL)AMINO]-4-(4-R-PHENYL)-4-OXOBUT-2-ENOIC ACIDS, HAVING ANALGESIC ACTIVITY	2012	Shipilovskikh Sergej Aleksandrovich Rubtsov Aleksandr Evgen'Evich Makhmudov Ramiz Ragibovich	RU2503671C1
N-[2-(5-ETHYL-1,3,4-THIADIAZOLYL)]AMIDE OF 2-(2-HYDROXYPHENYL)-2-OXOETHANE ACID, POSSESSING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY	2008	Pulina Natal'Ja Alekseevna Jushkov Vladimir Viktorovich Mokin Pavel Aleksandrovich Zalesov Vladimir Vasil'Evich Jatsenko Konstantin Vjacheslavovich	RU2364592C1
2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-yl)AMINO)-4-(4-METHOXYPHENYL)-4-OXOBUT-2-ENOIC ACID WITH ANTI-INFLAMMATORY ACTIVITY	2022	Shipilovskikh Sergei Aleksandrovich Makhmudov Ramiz Ragibovich Gorbunova Irina Aleksandrovna Sharaveva Iuliia Olegovna	RU2784434C1
N-R-AMIDES OF (Z)-2[(3-ETHOXYCARBONYL)-4,5,6,7-TETRAHYDROBENZO [b]THIEN-2-YL)AMINO]-4-PHENYL-4-OXOBUT-2-ENOIC ACIDS, HAVING ANALGESIC ACTIVITY	2012	Shipilovskikh Sergej Aleksandrovich Makhmudov Ramiz Ragibovich Rubtsov Aleksandr Evgen'Evich	RU2501795C1
BIS{3-PHENYL-1-[2-(5-METHYL-1,3,4-THIADIAZOLYL)]CARBOXAMIDO-1,3-PROPANEDIONATO}MANGANESE HAVING ANTI-INFLAMMATORY AND ANALGESIC ACTVITY	2008	Pulina Natal'Ja Alekseevna Jushkov Vladimir Viktorovich Sobin Fedor Vladimirovich Jatsenko Konstantin Vjacheslavovich Zalesov Vladimir Vasil'Evich	RU2396263C2
2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)AMINO)-4-(4-METHOXYPHENYL)-4-OXOBUTT-2-ENOIC ACID BENZYL ETHER WITH ANALGIC ACTIVITY	2022	Shipilovskikh Sergei Aleksandrovich Makhmudov Ramiz Ragibovich Gorbunova Irina Aleksandrovna Sharaveva Iuliia Olegovna	RU2798424C1

RU 2 348 613 C2

Authors

Pulina Natal'Ja Alekseevna

Zalesov Vladimir Vasil'Evich

Bystritskaja Oksana Anatol'Evna

Jushkov Vladimir Viktorovich

Jatsenko Konstantin Vjacheslavovich

Dates

2009-03-10—Published

2006-12-11—Filed