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2 485 112

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(51)

IPC

C07D333/38(2006-01-01)

A61K31/381(2006-01-01)

A61P29/00(2006-01-01)

(21) (22)

Application

2012117171/04, 2012-04-26

(24)

Start date

2012-04-26

(22)

Actual filing date

2012-04-26

(45)

Published

2013-06-20

(72)

Inventor

Makhmudov Ramiz RagibovichRubtsov Aleksandr Evgen'EvichShipilovskikh Sergej Aleksandrovich

(73)

Holder

Federal'Noe Gosudarstvennoe Bjudzhetnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennyj Natsional'Nyj Issledovatel'Skij Universitet"

4-(4-BROMOPHENYL)-4-OXO-2-{[3-ETHOXYCARBONYL)-4,5-DIMETHYLTHIEN-2-YL]AMINO}-2-BUTENOIC ACID, HAVING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY Russian patent published in 2013 - IPC C07D333/38 A61K31/381 A61P29/00

Abstract RU 2485112 C1

FIELD: chemistry.

SUBSTANCE: invention relates to organic chemistry and specifically to novel biologically active substances of the class of 4-aryl-2,4-dioxobutanoic acids. Disclosed is 4-(4-bromophenyl)-4-oxo-2-{[3-ethoxycarbonyl)-4,5-dimethylthien-2-yl]amino}-2-butenoic acid, having anti-inflammatory and analgesic activity, of formula (1): .

EFFECT: obtaining a compound with high output, having marked anti-inflammatory and analgesic activity as well as low toxicity.

1 cl, 1 tbl

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RU 2 485 112 C1

Authors

Makhmudov Ramiz Ragibovich

Rubtsov Aleksandr Evgen'Evich

Shipilovskikh Sergej Aleksandrovich

Dates

2013-06-20—Published

2012-04-26—Filed