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2 389 724

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IPC

C07D333/38(2006-01-01)

C07D333/78(2006-01-01)

A61K31/381(2006-01-01)

A61P29/00(2006-01-01)

(21) (22)

Application

2008151813/04, 2008-12-25

(24)

Start date

2008-12-25

(22)

Actual filing date

2008-12-25

(45)

Published

2010-05-20

(72)

Inventor

Shipilovskikh Sergej AleksandrovichRubtsov Aleksandr Evgen'EvichMakhmudov Ramiz RagipovichZalesov Vladimir Vasil'Evich

(73)

Holder

Gosudarstvennoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennyj Universitet"

4-(4-METHYLPHENYL)-4-OXO-2-[3-(ETHOXYCARBONYL-4,5-R,R-THIOPHEN-2-YLAMINO]BUT-2-ENOIC ACID, HAVING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY Russian patent published in 2010 - IPC C07D333/38 C07D333/78 A61K31/381 A61P29/00

Abstract RU 2389724 C1

FIELD: chemistry.

SUBSTANCE: invention relates to new biologically active substances and specifically to 4-(methylphenyl)-4-oxo-2-[3-ethoxycarbonyl-4,5-R²,R¹-thiophen-2-ylamino]but-2-enoic acid of general formula: R¹,R²=CH₃ R¹+R²=(CH₂)₃.

EFFECT: obtaining new compounds having anti-inflammatory and analgesic activity, as well as low toxicity, which can be used as medicinal agents.

1 cl, 1 tbl, 4 ex

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RU 2 389 724 C1

Authors

Shipilovskikh Sergej Aleksandrovich

Rubtsov Aleksandr Evgen'Evich

Makhmudov Ramiz Ragipovich

Zalesov Vladimir Vasil'Evich

Dates

2010-05-20—Published

2008-12-25—Filed