N'-(IMINO(2-((6-(2-METHOXYPHENYL)-2-(4-NITROBENZOYL)-3-OXO-2,3-DIHYDROPYRIDAZIN-4-YL)AMINO)-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-3-YL)METHYL)-4-NITROBENZOHYDRAZIDE, HAVING ANTI-INFLAMMATORY ACTIVITY Russian patent published in 2024 - IPC C07D409/12 A61K31/501 A61P29/00 

Abstract RU 2831250 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a novel biologically active N'-(imino(2-((6-(2-methoxyphenyl)-2-(4-nitrobenzoyl)-3-oxo-2,3-dihydropyridazin-4-yl)amino)-4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl)methyl)-4-nitrobenzohydrazide of formula

.

EFFECT: obtaining a compound with high output, having pronounced anti-inflammatory activity, as well as low toxicity.

1 cl, 1 tbl, 3 ex

Similar patents RU2831250C1

Title Year Author Number
4-BROMO-N'-((2-((2-(4-BROMOBENZOYL)-3-OXO-6-PHENYL-2,3-DIHYDROPYRIDAZIN-4-YL)AMINO)-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-3-YL)(IMINO)METHYL)BENZOHYDRAZIDE, HAVING ANALGESIC ACTIVITY 2024
  • Shipilovskikh Sergei Aleksandrovich
  • Makhmudov Ramiz Ragibovich
  • Lipin Dmitrii Vladimirovich
RU2829963C1
OBTAINING 2-((6-(2-METHOXYPHENYL)-3-OXO-2-ETHYL-2,3-DIHYDROPYRIDAZIN-4-YL)AMINO)-4,5,6,7-TETRAHYDROBENZO[b]THIOPHENE-3-CARBONITRILE WITH ANALGESIC ACTIVITY 2023
  • Shipilovskikh Sergei Aleksandrovich
  • Makhmudov Ramiz Ragibovich
  • Lipin Dmitrii Vladimirovich
RU2808995C1
2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-yl)AMINO)-4-(4-METHOXYPHENYL)-4-OXOBUT-2-ENOIC ACID WITH ANTI-INFLAMMATORY ACTIVITY 2022
  • Shipilovskikh Sergei Aleksandrovich
  • Makhmudov Ramiz Ragibovich
  • Gorbunova Irina Aleksandrovna
  • Sharaveva Iuliia Olegovna
RU2784434C1
1-(4-METHOXYPHENYL)2-(2-(4-NITROBENZOYL)HYDRASONO)-4-OXO-4-(4-METHYLPHENYL)BUTANOIC ACID ETHYL ETHER WITH ANTI-INFLAMMATORY ACTIVITY 2022
  • Shipilovskikh Sergei Aleksandrovich
  • Makhmudov Ramiz Ragibovich
  • Lipin Dmitrii Vladimirovich
  • Igidov Nazim Musabekovich
RU2798428C1
N-(5-BROMOPYRIDIN-2-YL)-4-OXO-4-(P-TOLYL)-2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL) )AMINO)BUT-2-ENAMIDE AS AN ANTI-INFLAMMATORY DRUG 2022
  • Shipilovskikh Sergei Aleksandrovich
  • Makhmudov Ramiz Ragibovich
  • Gorbunova Irina Aleksandrovna
  • Okoneshnikova Elizaveta Aleksandrovna
RU2798426C1
2-((6-(4-BROMOPHENYL)-3-OXO-2,3-DIHYDROPYRIDAZIN-4-YL)AMINO)-4,5,6,7-TETRAHYDROBENZO[b]THIOPHENE-3-CARBONITRILE, HAVING ANTIMICROBIAL ACTIVITY WITH RESPECT TO CANDIDA ALBICANS 2024
  • Shipilovskikh Sergei Aleksandrovich
  • Makhmudov Ramiz Ragibovich
  • Lipin Dmitrii Vladimirovich
RU2829463C1
1-AMINO-1,6-DIOXO-6-(4-CHLOROPHENYL)-2-CYANO-4-(3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)AMINO)HEXA -2,4-DIEN-3-OLATE POTASSIUM WITH ANTI-INFLAMMATORY ACTIVITY 2022
  • Shipilovskikh Sergei Aleksandrovich
  • Makhmudov Ramiz Ragibovich
  • Lipin Dmitrii Vladimirovich
  • Kozlov Danil Anatolevich
RU2798468C1
N-ETHYL-2-((3-OXO-6-(4-FLUOROPHENYL)-2-ETHYL-2,3-DIHYDROPYRIDAZIN-4-YL)AMINO)-4,5,6,7-TETRAHYDROBENZO[b]THIOPHENE-3-CARBOXIMIDE HYDRAZIDE, HAVING ANTIMICROBIAL ACTIVITY 2024
  • Shipilovskikh Sergei Aleksandrovich
  • Makhmudov Ramiz Ragibovich
  • Lipin Dmitrii Vladimirovich
RU2831253C1
1-PHENYLETHYL ETHER OF 2-(2-(4-NITROBENZOYL)HYDRAZONO)-4-OXO-4-(4-METHYLPHENYL)BUTANOIC ACID WITH ANALGESIC ACTIVITY 2022
  • Shipilovskikh Sergei Aleksandrovich
  • Makhmudov Ramiz Ragibovich
  • Lipin Dmitrii Vladimirovich
  • Igidov Nazim Musabekovich
RU2798430C1
2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)AMINO)-4-(4-METHOXYPHENYL)-4-OXOBUTT-2-ENOIC ACID BENZYL ETHER WITH ANALGIC ACTIVITY 2022
  • Shipilovskikh Sergei Aleksandrovich
  • Makhmudov Ramiz Ragibovich
  • Gorbunova Irina Aleksandrovna
  • Sharaveva Iuliia Olegovna
RU2798424C1

RU 2 831 250 C1

Authors

Shipilovskikh Sergej Aleksandrovich

Makhmudov Ramiz Ragibovich

Lipin Dmitrij Vladimirovich

Dates

2024-12-03Published

2024-04-04Filed