METHOD OF ADJUVANT THERAPY OF STOMACH CANCER Russian patent published in 2012 - IPC A61N5/00 A61M1/36 A61K31/513 A61K35/16 A61P35/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to oncology, and may be used in integrated treatment of stomach cancer. That is ensured by a surgical intervention to place a microirrigator into an abdominal cavity. Then 4 weeks after the surgery, blood 300 ml is taken on the first day to be centrifuged and to recover autoplasma. Autoplasma and chemopreparations are placed into a first flask, autoplasma - into second and third flasks, blood corpuscles and chemopreparations - into a forth force. The 2^nd and 3^rd flasks are frozen, the 1^st and 4^th flasks are separately incubated for 40 minutes at 37°C. The incubated blood corpuscles and chemopreparations from the 4^th flask are introduced intravenously drop-by-drop. Autoplasma and chemopreparations from the 1^st flask are introduced intraperitoneally through the microirrigator. It is followed by 1 session of radiation therapy on the abdominal cavity at single dose 2 Gy. On the 2^nd and 4^th therapeutic days, only sessions of radiation therapy are applied. On the 3^rd and 5^th days, the sessions of radiation therapy are preceded by freezing one flask with autoplasma added with chemopreparations, and the flasks are incubated for 40 minutes at 37°C. Then autoplasma and chemopreparations are introduced intraperitoneally through the microirrgator, and the session of radiation therapy is conducted. On the 6^th and 7^th days, a pause is made. Starting from 8th and 15th days, a five-day therapeutic course is repeated.

EFFECT: method enables reducing rate of metastases in the peritoneum caused by stomach cancer and increasing survival rate of the patients due to combined surgical and chemoradiation therapy in a certain mode.

2 ex