FIELD: chemistry.
SUBSTANCE: novel crystalline form of topotecan monohydrochloride pentahydrate is pentahydrate of 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4': 6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dione monohydrochloride, as well as to preparation method, corresponding pharmaceutical compositions.
EFFECT: possibility of using claimed invention to treat anti-viral and cancer-related diseases.
23 cl, 3 dwg, 2 tbl, 3 ex
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