FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to pharmaceutics and can be used for making the preparation referred to chondroprotective agents used for curing degenerative atrhronosos and spinal disorders. The medical product contains chondroitin sulphate; dimethyl sulfoxide; preserving agent, emulgel base. The preserving agent is mixed Nipagin and Nipasol. The emulgel base is mixed thickening agent, solvent and softener. The thickening agent of the emulgel base is acrylic and methacrylic acid copolymers as Carbomer; the solvent is water, and the softener is mineral or vegetable oil. Additionally is contains: Carbomer neutraliser as an inorganic or organic base; coemulsifier as a nonionic surface-active substance, namely oleic acid monoester and polyoxyethylated sorbitan (TWIN 80). Optionally it contains essential oil in ratio, wt %: chondroitin sulphate 1-10 dimethyl sulfoxide 5-15 Nipagin 0.1-0.3; Nipasol 0.05-0.15; Carbomer 1-5; Mineral or vegetable oil 5-15; Twin 80 1-15; Inorganic or organic base 1-5; Essential oil 0.05-0.25; Treated water 100.0%. In certain cases the medical product can contain olive oil as a softener, inorganic base, namely sodium hydroxide or sodium bicarbonate as Carbomer neutraliser. Besides as Carbomer neutraliser it can contain organic base, namely triethanolamine. The medical product is to contain neroli oil as the essential oil preferentially.
EFFECT: invention ensures softening action, provides formulation stability and optimum fluidity, improves adhesiveness of the preparation, accelerates penetration of the active substances through skin barrier, and intensifies anti-inflammatory action.
6 cl, 3 ex, 6 tbl
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Authors
Dates
2009-04-27—Published
2007-04-18—Filed