METHOD OF OBTAINING MOLECULAR COMPLEXES Russian patent published in 2009 - IPC A61K47/48 A61K9/14 A61K9/16 

FIELD: chemistry.

SUBSTANCE: method of obtaining soluble molecular complexes, containing one or several acting substances, poorly soluble in water medium, included into one or several host molecules representing cyclodextrin, which is distinguished by the fact that it includes following stages: (a) bringing one or several acting substances in contact with one or several host-molecules; (b) carrying out stage of molecular diffusion by bringing liquid liquefied under pressure in contact in static conditions with mixture obtained at stage (a), in presence of one or several agents favouring diffusion; (c) isolation of thus obtained molecular complex. Carrying out stage of molecular diffusion also favours dissolution in water medium with increase of solubility approximately by 100 fold.

EFFECT: method, including stage of molecular diffusion in static conditions applying liquid liquefied under pressure, excluding stage of further washing with liquid with supercritical parameters, considerably increases part of including depending on amount of favouring diffusion agent, added to medium.

6 cl, 7 ex