FIELD: chemistry.
SUBSTANCE: invention relates to a method of preparing a soluble inclusion compound which contains one or more active substances which are partially soluble in aqueous medium, included in one or more host molecules, distinguished by that it includes the following sequence of steps: one or more active substances are brought into contact with one or more host molecules which are cyclodextrins; molecular diffusion is carried out by bringing dense fluid medium which is carbon dioxide under pressure into contact with a mixture obtained at the previous step in static mode in the presence of one or more diffusion agents; the formed active substance/host molecule molecular complex is separated; an agent for reaction with a complex is added to the active substance/host molecule molecular complex and mixed and the solid inclusion compound formed is separated.
EFFECT: improvement of method.
8 cl, 17 dwg, 3 tbl, 8 ex
| Title |
Year |
Author |
Number |
| METHOD OF OBTAINING MOLECULAR COMPLEXES |
2004 |
- Loshar Juber
- Soso Mars'Jal'
- Fress Bernar
|
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|
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|
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2003 |
|
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2001 |
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|
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2009 |
|
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2005 |
|
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1993 |
- Valentino Zh.Stella
- Rodzher Raevski
|
RU2113442C1 |
| CRYSTALLINE COMPLEX OF CYCLODEXTRIN WITH RANITIDIN HYDROCHLORIDE, METHOD OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEREOF |
1994 |
- Vil'Frid Fisher
- Karin Klokkers
|
RU2143896C1 |
| COMPLEX INCLUDING N-ETHOXYCARBONYL-3- MORPHOLINESYDNONEIMINE OR SALT THEREOF WITH CYCLODEXRIN OR CYLODEXTRIN DERIVATIVE, METHOD OF PREPARING SAID INCLUSION CONTEX, PHARMACEUTICAL COMPOSITIONS AND METHOD OF PREPARATION THEREOF, AND TREATMENT METHOD |
1991 |
- Marija Vikmon[Hu]
- Jozhef Sejtli[Hu]
- Jozhef Gaal[Hu]
- Ishtvan Khermets[Hu]
- Agnesh Khorvat[Hu]
- Katalin Marmaroshi[Hu]
- Gabor Khorvat[Hu]
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|
RU2111216C1 |
