FIELD: pharmaceutical technology, pharmacy.
SUBSTANCE: invention relates to a method for preparing the inclusion compound of piroxicam with β-cyclodextrin. Method involves freezing process of aqueous solution of two components before drying at very high rate. Prepared products show physicochemical properties and technological and biopharmaceutical properties that display advantage properties as compared with properties prepared by methods of preceding practice. Solubility of piroxicam in tablets prepared by the proposed method is ≥90% for 10 minutes. Prepared products are useful for preparing pharmaceutical compositions for oral administration.
EFFECT: improved preparing method, improved properties.
13 cl, 2 dwg, 2 ex
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