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2 461 563

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IPC

C07J63/00(2006-01-01)

C07J43/00(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2011129988/04, 2011-07-19

(24)

Start date

2011-07-19

(22)

Actual filing date

2011-07-19

(45)

Published

2012-09-20

(72)

Inventor

Sorokina Irina Vasil'EvnaTolstikova Tat'Jana GenrikhovnaZhukova Tat'Jana Anatol'EvnaBessergeneva Ekaterina PavlovnaMajnagashev Il'Ja JakovlevichSalakhutdinov Nariman FaridovichTolstikov Genrikh Aleksandrovich

(73)

Holder

Federal'Noe Gosudarstvennoe Bjudzhetnoe Uchrezhdenie Nauki Novosibirskij Institut Organicheskoj Khimii Im. N.N. Vorozhtsova Sibirskogo Otdelenija Rossijskoj Akademii Nauk So Ran)

N-[3-OXO-LUPANO-28-YL]-MORPHOLINE - AGENT FOR CORRECTION OF CYTOTOXIC LIVER DAMAGES WITH ANTITUMOUR AND ANTIMETASTATIC ACTIVITY Russian patent published in 2012 - IPC C07J63/00 C07J43/00 A61P35/00

Abstract RU 2461563 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a chemical compound, namely N-[3-oxo-lupano-28-yl]-morpholine of formula (1): possessing antitumour and antimetastatic activity and representing a corrector of hepatotoxic damages caused by a tumour process and cytostatic polychemotherapy, and may be applicable in medicine as a pharmaceutic agent for reducing manifestation of morphological liver damages accompanying oncological diseases, including as a part of the integrated antitumour therapy.

EFFECT: preparation of the chemical compound possessing antitumour and antimetastatic activity.

1 cl, 10 ex, 6 tbl, 3 dwg

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RU 2 461 563 C1

Authors

Sorokina Irina Vasil'Evna

Tolstikova Tat'Jana Genrikhovna

Zhukova Tat'Jana Anatol'Evna

Bessergeneva Ekaterina Pavlovna

Majnagashev Il'Ja Jakovlevich

Salakhutdinov Nariman Faridovich

Tolstikov Genrikh Aleksandrovich

Dates

2012-09-20—Published

2011-07-19—Filed