FIELD: pharmacology.
SUBSTANCE: invention relates to pharmaceutical industry, in particular to medicinal form protected against non-intended use. Protected against non-intended use thermally formed without extrusion medicinal form, which together with one or two active substances (A), which are potential object of their non-medicinal use, as well as with physiologically compatible auxiliary substances (B) contains definite synthetic or natural polymer (C) and optionally wax (D), component (C) and possibly present component (D) are contained in medicinal form in definite amounts. Method of preparing medicinal form, in which without application of extruder components (A), (B), (C) and possibly used component (D) are mixed together, and also with them or if necessary separately possibly used components (a)-(f) are mixed with addition of component (C) and possibly used component (D), and from obtained mixture or from obtained mixtures, in some cases after its, or respectively their granulation, by applying force with preliminary or simultaneous heat impact medicinal form is formed. Medicinal form obtained by definite method.
EFFECT: efficient protection against non-intended use.
29 cl, 1 dwg, 8 ex
Title | Year | Author | Number |
---|---|---|---|
DRUG DOSAGE FORM, PROTECTED FROM UNINTENDED APPLICATION | 2004 |
|
RU2339365C2 |
PROTECTED AGAINST UNADMINISTERED APPLICATION PERORAL MEDICATION FORM | 2005 |
|
RU2396944C2 |
DOSAGE FORM PROTECTED FROM UNINTENDED USE AND CONTAINING (1R, 2R)-3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYLPROPYL)PHENOL | 2005 |
|
RU2393847C2 |
SELF-REGULATED RELEASE OF ACTIVE PHARMACEUTICAL INGREDIENT | 2013 |
|
RU2673818C2 |
COMPOSITION FOR THE TREATMENT OF VEISALGIA | 2017 |
|
RU2757379C2 |
DEGRADATION-RESISTANT DOSAGE FORM WITH DELAYED RELEASE OF OXYCODONE HYDROCHLORIDE | 2010 |
|
RU2461381C2 |
EXTENDED RELEASE DURABLE DOSAGE FORMS | 2006 |
|
RU2399371C2 |
MEDICINAL RETARD-FORMULATION CONTAINING TRAMADOL SACCHARINATE | 2000 |
|
RU2292877C2 |
ANALGESIC DRUG WITH SUSTAINED-RELEASING ACTIVE SUBSTANCE | 2000 |
|
RU2244541C2 |
PHARMACEUTICAL COMPOSITION CONSISTING OF MULTIPLE SUBUNITS AND METHOD OF ITS PREPARING | 1997 |
|
RU2201223C2 |
Authors
Dates
2009-05-10—Published
2004-08-05—Filed