MEDICINAL FORM PROTECTED AGAINST NON-INTENDED USE Russian patent published in 2009 - IPC A61K9/20 A61K31/485 A61K31/515 A61K31/5513 

Abstract RU 2354357 C2

FIELD: pharmacology.

SUBSTANCE: invention relates to pharmaceutical industry, in particular to medicinal form protected against non-intended use. Protected against non-intended use thermally formed without extrusion medicinal form, which together with one or two active substances (A), which are potential object of their non-medicinal use, as well as with physiologically compatible auxiliary substances (B) contains definite synthetic or natural polymer (C) and optionally wax (D), component (C) and possibly present component (D) are contained in medicinal form in definite amounts. Method of preparing medicinal form, in which without application of extruder components (A), (B), (C) and possibly used component (D) are mixed together, and also with them or if necessary separately possibly used components (a)-(f) are mixed with addition of component (C) and possibly used component (D), and from obtained mixture or from obtained mixtures, in some cases after its, or respectively their granulation, by applying force with preliminary or simultaneous heat impact medicinal form is formed. Medicinal form obtained by definite method.

EFFECT: efficient protection against non-intended use.

29 cl, 1 dwg, 8 ex

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RU 2 354 357 C2

Authors

Bartolomehus Iogannes

Kugel'Mann Genrikh

Arkenau-Marits Ehlizabet

Dates

2009-05-10Published

2004-08-05Filed