FIELD: chemistry.
SUBSTANCE: invention concerns organic chemistry, particularly method of obtaining 6-hydroxyspiro[3,4]octane-6-alkylcarboxylates (1), 
R=C2H5, n-C4H9, where methylenecyclobutane undergoes interaction with triethylaluminum (AlEt3) in the presence of zirconacene dichloride catalyst Cp2ZrCl2 at molar ratio of methylenecyclobutane:AlEt3:Cp2ZrCl2=10:(12-16):(0.5-0.9), in argon atmosphere at room temperature and atmospheric pressure in hexane for 4 hours, with further addition of copper bromide catalyst (CuBr) in amount of 10-14 molar % in respect of methylenecyclobutane, and dialkyl ether of oxalic acid thrice exceeding amount of AlEt3, to reaction mass at -15°C, followed by stirring of reaction mass at room temperature with further acid hydrolysis of reaction mass.
EFFECT: 6-hydroxyspiro[3,4]octane-6-alkylcarboxylates applicable in fine organic synthesis and production of paint coating materials and bioactive substances, with total 76-95% output of end product after reaction mass hydrolysis.
1 ex, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| SPIRO[3,4]OCTAN-6-OL SYNTHESIS METHOD | 2007 |
|
RU2378245C2 |
| METHOD OF SPIRO[3,4]OCT-6-YLFORMIATE OBTAINMENT | 2007 |
|
RU2355676C2 |
| METHOD OF OBTAINING 6-THIASPIRO[3,4]OCTANE | 2007 |
|
RU2368606C2 |
| METHOD OF 6-ETHYL-6-ALUMINASPIRO[3,4] OCTANE | 2007 |
|
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|
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|
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|
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| METHOD FOR PREPARING 2,3-FULLERENO[60]CYCLOPENTANOLS | 2003 |
|
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| METHOD OF PRODUCING exo-TRICYCLO[4,2,1,0]NONANE-3-SPIRO-1'-(3'-THIA)CYCLOPENTANE | 2008 |
|
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| OPTICALLY ACTIVE 3-ALKYL-1-HYDROXY-1'S-METHYLCYCLOPENTANOL SYNTHESIS METHOD | 2008 |
|
RU2400466C2 |
