FIELD: chemistry.
SUBSTANCE: method of obtaining 6-thiaspiro[3,4]octane can be used in fine organic synthesis, in production of oil additives and biologically active substances. The method involves reacting methylenecyclobutane with triethylaluminium (AlEt3) in the presence of a catalyst in an argon atmosphere at room temperature and atmospheric pressure in hexane for 4 hours with subsequent addition to the reaction mass at temperature -40°C of thionyl chloride, taken in equimolar amount with respect to AIEt3 and stirring at that temperature for 6-8 hours.
EFFECT: output of the desired product after hydrolysis of the reaction mass is 53-74%.
1 tbl, 7 ex
| Title | Year | Author | Number |
|---|---|---|---|
| SPIRO[3,4]OCTAN-6-OL SYNTHESIS METHOD | 2007 |
|
RU2378245C2 |
| METHOD OF 6-HYDROXYSPIRO[3,4]OCTANE-6-ALKYLCARBOXYLATES OBTAINMENT | 2007 |
|
RU2355677C1 |
| METHOD OF SPIRO[3,4]OCT-6-YLFORMIATE OBTAINMENT | 2007 |
|
RU2355676C2 |
| METHOD OF 6-ETHYL-6-ALUMINASPIRO[3,4] OCTANE | 2007 |
|
RU2342392C2 |
| METHOD OF PRODUCING exo-TRICYCLO[4,2,1,0]NONANE-3-SPIRO-1'-(3'-THIA)CYCLOPENTANE | 2008 |
|
RU2408590C2 |
| METHOD OF SPIRO[3,3]HEPTANE PRODUCTION | 2007 |
|
RU2350595C1 |
| METHOD FOR PREPARING 3-THIA-EXSO-TRICYCLO-[5.2.1.0]-DECANE | 2002 |
|
RU2213742C1 |
| METHOD OF PRODUCING 1-FLUORO-2,3-DIALKYLBOROCYCLOPENT-2-ENES | 2011 |
|
RU2478641C2 |
| METHOD OF PRODUCING TRICYCLO[4,2,1,0]-NONANE-3-SPIRO-1'-BUTANE | 2008 |
|
RU2373174C1 |
| METHOD OF PRODUCING 1-FLUORO-3-ALKYLBOROCYCLOPENTANES | 2010 |
|
RU2440356C2 |
